Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells.

Osorio, Fabiola; Tavernier, Simon J; Hoffmann, Eik; Saeys, Yvan; Martens, Liesbet; Vetters, Jessica; Delrue, Iris; De Rycke, Riet; Parthoens, Eef; Pouliot, Philippe; Iwawaki, Takao; Janssens, Sophie; Lambrecht, Bart N.

Nat Immunol ; 15(3): 248-57, 2014 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-24441789

2.

Tirap controls Mycobacterium tuberculosis phagosomal acidification.

Belhaouane, Imène; Pochet, Amine; Chatagnon, Jonathan; Hoffmann, Eik; Queval, Christophe J; Deboosère, Nathalie; Boidin-Wichlacz, Céline; Majlessi, Laleh; Sencio, Valentin; Heumel, Séverine; Vandeputte, Alexandre; Werkmeister, Elisabeth; Fievez, Laurence; Bureau, Fabrice; Rouillé, Yves; Trottein, François; Chamaillard, Mathias; Brodin, Priscille; Machelart, Arnaud.

PLoS Pathog ; 19(3): e1011192, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36888688

3.

Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages.

van de Laar, Lianne; Saelens, Wouter; De Prijck, Sofie; Martens, Liesbet; Scott, Charlotte L; Van Isterdael, Gert; Hoffmann, Eik; Beyaert, Rudi; Saeys, Yvan; Lambrecht, Bart N; Guilliams, Martin.

Immunity ; 44(4): 755-68, 2016 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-26992565

4.

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice.

Belouzard, Sandrine; Machelart, Arnaud; Sencio, Valentin; Vausselin, Thibaut; Hoffmann, Eik; Deboosere, Nathalie; Rouillé, Yves; Desmarets, Lowiese; Séron, Karin; Danneels, Adeline; Robil, Cyril; Belloy, Loic; Moreau, Camille; Piveteau, Catherine; Biela, Alexandre; Vandeputte, Alexandre; Heumel, Séverine; Deruyter, Lucie; Dumont, Julie; Leroux, Florence; Engelmann, Ilka; Alidjinou, Enagnon Kazali; Hober, Didier; Brodin, Priscille; Beghyn, Terence; Trottein, François; Deprez, Benoit; Dubuisson, Jean.

PLoS Pathog ; 18(5): e1010498, 2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-35587469

5.

Toll-like Receptor 4 Engagement on Dendritic Cells Restrains Phago-Lysosome Fusion and Promotes Cross-Presentation of Antigens.

Alloatti, Andrés; Kotsias, Fiorella; Pauwels, Anne-Marie; Carpier, Jean-Marie; Jouve, Mabel; Timmerman, Evy; Pace, Luigia; Vargas, Pablo; Maurin, Mathieu; Gehrmann, Ulf; Joannas, Leonel; Vivar, Omar I; Lennon-Duménil, Ana-Maria; Savina, Ariel; Gevaert, Kris; Beyaert, Rudi; Hoffmann, Eik; Amigorena, Sebastian.

Immunity ; 43(6): 1087-100, 2015 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-26682983

6.

Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice.

Demars, Aurore; Vitali, Armelle; Comein, Audrey; Carlier, Elodie; Azouz, Abdulkader; Goriely, Stanislas; Smout, Justine; Flamand, Véronique; Van Gysel, Mégane; Wouters, Johan; Abendroth, Jan; Edwards, Thomas E; Machelart, Arnaud; Hoffmann, Eik; Brodin, Priscille; De Bolle, Xavier; Muraille, Eric.

PLoS Pathog ; 17(9): e1009887, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34525130

7.

The UPR sensor IRE1α promotes dendritic cell responses to control Toxoplasma gondii infection.

Poncet, Anaïs F; Bosteels, Victor; Hoffmann, Eik; Chehade, Sylia; Rennen, Sofie; Huot, Ludovic; Peucelle, Véronique; Maréchal, Sandra; Khalife, Jamal; Blanchard, Nicolas; Janssens, Sophie; Marion, Sabrina.

EMBO Rep ; 22(3): e49617, 2021 03 03.

Artigo em Inglês | MEDLINE | ID: mdl-33586853

8.

Spatiotemporal Changes of the Phagosomal Proteome in Dendritic Cells in Response to LPS Stimulation.

Pauwels, Anne-Marie; Härtlova, Anetta; Peltier, Julien; Driege, Yasmine; Baudelet, Griet; Brodin, Priscille; Trost, Matthias; Beyaert, Rudi; Hoffmann, Eik.

Mol Cell Proteomics ; 18(5): 909-922, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30808727

9.

Patterns, Receptors, and Signals: Regulation of Phagosome Maturation.

Pauwels, Anne-Marie; Trost, Matthias; Beyaert, Rudi; Hoffmann, Eik.

Trends Immunol ; 38(6): 407-422, 2017 06.

Artigo em Inglês | MEDLINE | ID: mdl-28416446

10.

ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton.

Song, Ok-Ryul; Queval, Christophe J; Iantomasi, Raffaella; Delorme, Vincent; Marion, Sabrina; Veyron-Churlet, Romain; Werkmeister, Elisabeth; Popoff, Michka; Ricard, Isabelle; Jouny, Samuel; Deboosere, Nathalie; Lafont, Frank; Baulard, Alain; Yeramian, Edouard; Marsollier, Laurent; Hoffmann, Eik; Brodin, Priscille.

EMBO Rep ; 19(1): 29-42, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-29141986

11.

T(oo)bAd.

Brodin, Priscille; Hoffmann, Eik.

Nat Chem Biol ; 15(9): 849-850, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31427816

12.

Autonomous phagosomal degradation and antigen presentation in dendritic cells.

Hoffmann, Eik; Kotsias, Fiorella; Visentin, Géraldine; Bruhns, Pierre; Savina, Ariel; Amigorena, Sebastian.

Proc Natl Acad Sci U S A ; 109(36): 14556-61, 2012 Sep 04.

Artigo em Inglês | MEDLINE | ID: mdl-22908282

13.

Dynamin A, Myosin IB and Abp1 couple phagosome maturation to F-actin binding.

Gopaldass, Navin; Patel, Devang; Kratzke, Ramona; Dieckmann, Regis; Hausherr, Stéphanie; Hagedorn, Monica; Monroy, Roger; Krüger, Julia; Neuhaus, Eva M; Hoffmann, Eik; Hille, Katja; Kuznetsov, Sergei A; Soldati, Thierry.

Traffic ; 13(1): 120-30, 2012 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-22008230

14.

Ezrin promotes actin assembly at the phagosome membrane and regulates phago-lysosomal fusion.

Marion, Sabrina; Hoffmann, Eik; Holzer, Daniela; Le Clainche, Christophe; Martin, Marianne; Sachse, Martin; Ganeva, Iva; Mangeat, Paul; Griffiths, Gareth.

Traffic ; 12(4): 421-37, 2011 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-21210911

15.

Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium.

van Wijk, Rob C; Lucía, Ainhoa; Sudhakar, Pavan Kumar; Sonnenkalb, Lindsay; Gaudin, Cyril; Hoffmann, Eik; Dremierre, Bérénice; Aguilar-Ayala, Diana Angélica; Molin, Michael Dal; Rybniker, Jan; de Giorgi, Stefano; Cioetto-Mazzabò, Laura; Segafreddo, Greta; Manganelli, Riccardo; Degiacomi, Giulia; Recchia, Deborah; Pasca, Maria Rosalia; Simonsson, Ulrika S H; Ramón-García, Santiago.

iScience ; 26(4): 106411, 2023 Apr 21.

Artigo em Inglês | MEDLINE | ID: mdl-37091238

16.

Infection and immunity: 'There Are Things Out There You (Don't) Need To Know About'.

Afonina, Inna S; Hoffmann, Eik.

FEBS J ; 289(14): 3920-3925, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35852038

17.

A reporter cell line for the automated quantification of SARS-CoV-2 infection in living cells.

Desmarets, Lowiese; Callens, Nathalie; Hoffmann, Eik; Danneels, Adeline; Lavie, Muriel; Couturier, Cyril; Dubuisson, Jean; Belouzard, Sandrine; Rouillé, Yves.

Front Microbiol ; 13: 1031204, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36246297

18.

Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters.

Briand, François; Sencio, Valentin; Robil, Cyril; Heumel, Séverine; Deruyter, Lucie; Machelart, Arnaud; Barthelemy, Johanna; Bogard, Gemma; Hoffmann, Eik; Infanti, Fabrice; Domenig, Oliver; Chabrat, Audrey; Richard, Virgile; Prévot, Vincent; Nogueiras, Ruben; Wolowczuk, Isabelle; Pinet, Florence; Sulpice, Thierry; Trottein, François.

Viruses ; 14(9)2022 09 17.

Artigo em Inglês | MEDLINE | ID: mdl-36146875

19.

Alteration of the gut microbiota following SARS-CoV-2 infection correlates with disease severity in hamsters.

Sencio, Valentin; Machelart, Arnaud; Robil, Cyril; Benech, Nicolas; Hoffmann, Eik; Galbert, Chloé; Deryuter, Lucie; Heumel, Séverine; Hantute-Ghesquier, Aline; Flourens, Anne; Brodin, Priscille; Infanti, Fabrice; Richard, Virgile; Dubuisson, Jean; Grangette, Corinne; Sulpice, Thierry; Wolowczuk, Isabelle; Pinet, Florence; Prévot, Vincent; Belouzard, Sandrine; Briand, François; Duterque-Coquillaud, Martine; Sokol, Harry; Trottein, François.

Gut Microbes ; 14(1): 2018900, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-34965194

20.

High-Content Analysis Monitoring Intracellular Trafficking and Replication of Mycobacterium tuberculosis Inside Host Cells.

Deboosere, Nathalie; Belhaouane, Imène; Machelart, Arnaud; Hoffmann, Eik; Vandeputte, Alexandre; Brodin, Priscille.

Methods Mol Biol ; 2314: 649-702, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34235675

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